Pseudomonas aeruginosa UCBPP-PA14, PA14_62200 (mrcB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00905
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009274 peptidoglycan-based cell wall
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008233 peptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008955 peptidoglycan glycosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046677 response to antibiotic
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF56601 beta-lactamase/transpeptidase-like IPR012338 Beta-lactamase/transpeptidase-like 319 756 4.7E-119
Pfam PF14814 Bifunctional transglycosylase second domain IPR028166 Bifunctional transglycosylase second domain 71 154 8.5E-25
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 61 725 0.0
Gene3D G3DSA:3.30.2060.10 - - - 69 157 0.0
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 431 659 5.5E-18
NCBIfam TIGR02071 JCVI: penicillin-binding protein 1B IPR011813 Penicillin-binding protein 1B 26 752 0.0
FunFam G3DSA:3.40.710.10:FF:000006 Penicillin-binding protein 1B - - 355 725 0.0
PIRSF PIRSF002799 PBP1b IPR011813 Penicillin-binding protein 1B 1 774 0.0
Gene3D G3DSA:1.20.5.100 - - - 18 54 3.0E-6
SUPERFAMILY SSF53955 Lysozyme-like IPR023346 Lysozyme-like domain superfamily 163 360 3.94E-66
Pfam PF00912 Transglycosylase IPR001264 Glycosyl transferase, family 51 166 336 1.4E-56
FunFam G3DSA:1.10.3810.10:FF:000002 Penicillin-binding protein 1B - - 158 361 1.7E-81
PANTHER PTHR32282 BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED - - 4 763 0.0
Gene3D G3DSA:1.10.3810.10 - IPR036950 Penicillin binding protein transglycosylase domain 158 361 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.