Pseudomonas aeruginosa UCBPP-PA14, PA14_62580 (panB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00222
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0015940 pantothenate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00222
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51621
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00770 Pantothenate and CoA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00222 JCVI: 3-methyl-2-oxobutanoate hydroxymethyltransferase IPR003700 Ketopantoate hydroxymethyltransferase 4 264 2.3E-99
PIRSF PIRSF000388 PanB IPR003700 Ketopantoate hydroxymethyltransferase 2 266 1.2E-97
CDD cd06557 KPHMT-like IPR003700 Ketopantoate hydroxymethyltransferase 6 258 0.0
FunFam G3DSA:3.20.20.60:FF:000003 3-methyl-2-oxobutanoate hydroxymethyltransferase - - 1 266 4.1E-112
PANTHER PTHR20881 3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE IPR003700 Ketopantoate hydroxymethyltransferase 2 264 1.5E-93
Pfam PF02548 Ketopantoate hydroxymethyltransferase IPR003700 Ketopantoate hydroxymethyltransferase 4 259 3.8E-105
Gene3D G3DSA:3.20.20.60 - IPR040442 Pyruvate kinase-like domain superfamily 1 264 2.2E-113
Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. IPR003700 Ketopantoate hydroxymethyltransferase 4 264 41.26918
SUPERFAMILY SSF51621 Phosphoenolpyruvate/pyruvate domain IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily 4 264 1.94E-101

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.