Pseudomonas aeruginosa UCBPP-PA14, PA14_62940 (dapB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008839 4-hydroxy-tetrahydrodipicolinate reductase
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000161
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000161
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00300 Lysine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Lysine biosynthesis ECO:0000037
not_recorded
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00261 Monobactam biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00036 JCVI: 4-hydroxy-tetrahydrodipicolinate reductase IPR023940 Dihydrodipicolinate reductase 3 266 4.9E-100
PANTHER PTHR20836 DIHYDRODIPICOLINATE REDUCTASE IPR023940 Dihydrodipicolinate reductase 4 265 2.6E-50
FunFam G3DSA:3.40.50.720:FF:000048 4-hydroxy-tetrahydrodipicolinate reductase - - 2 131 3.9E-46
SUPERFAMILY SSF55347 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain - - 128 237 1.79E-37
FunFam G3DSA:3.30.360.10:FF:000004 4-hydroxy-tetrahydrodipicolinate reductase - - 128 235 1.3E-54
Pfam PF01113 Dihydrodipicolinate reductase, N-terminus IPR000846 Dihydrodipicolinate reductase, N-terminal 3 126 1.5E-39
Pfam PF05173 Dihydrodipicolinate reductase, C-terminus IPR022663 Dihydrodipicolinate reductase, C-terminal 129 265 6.8E-44
Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. IPR023940 Dihydrodipicolinate reductase 2 265 36.423985
PIRSF PIRSF000161 DHPR IPR023940 Dihydrodipicolinate reductase 1 268 3.9E-88
Gene3D G3DSA:3.30.360.10 Dihydrodipicolinate Reductase; domain 2 - - 128 235 1.3E-118
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 1 267 3.23E-50
Gene3D G3DSA:3.40.50.720 - - - 3 265 1.3E-118

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.