Pseudomonas aeruginosa UCBPP-PA14, PA14_63090 (lldD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01070
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0010181 FMN binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01559
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006089 lactate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01559
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004457 lactate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01559
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.20.20.70:FF:000029 L-lactate dehydrogenase - - 2 380 0.0
Pfam PF01070 FMN-dependent dehydrogenase IPR000262 FMN-dependent dehydrogenase 13 375 3.6E-125
SUPERFAMILY SSF51395 FMN-linked oxidoreductases - - 7 374 8.55E-98
PIRSF PIRSF000138 Al-hdrx_acd_dh IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent 2 379 5.6E-122
PANTHER PTHR10578 S -2-HYDROXY-ACID OXIDASE-RELATED - - 5 376 2.6E-103
CDD cd02809 alpha_hydroxyacid_oxid_FMN IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent 8 371 0.0
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 3 379 2.3E-123
Hamap MF_01559 L-lactate dehydrogenase [lldD]. IPR020920 L-lactate dehydrogenase, bacterial 1 380 74.959404
NCBIfam NF033901 NCBIFAM: FMN-dependent L-lactate dehydrogenase LldD IPR020920 L-lactate dehydrogenase, bacterial 1 377 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.