Pseudomonas aeruginosa UCBPP-PA14, PA14_71600 (purK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004638 phosphoribosylaminoimidazole carboxylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01928
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006189 'de novo' IMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01928
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51246 Rudiment single hybrid motif IPR011054 Rudiment single hybrid motif 297 356 1.26E-13
FunFam G3DSA:3.40.50.20:FF:000016 N5-carboxyaminoimidazole ribonucleotide synthase - - 1 101 3.8E-48
SUPERFAMILY SSF52440 PreATP-grasp domain IPR016185 Pre-ATP-grasp domain superfamily 2 94 2.45E-22
Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 344 39.176777
Gene3D G3DSA:3.30.1490.20 - IPR013815 ATP-grasp fold, subdomain 1 102 175 2.6E-26
Gene3D G3DSA:3.30.470.20 - - - 176 360 3.5E-62
NCBIfam TIGR01161 JCVI: 5-(carboxyamino)imidazole ribonucleotide synthase IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 348 3.8E-108
PANTHER PTHR11609 PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7 - - 2 357 1.3E-109
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like - - 97 292 2.47E-56
Gene3D G3DSA:3.40.50.20 - - - 1 101 7.7E-33
Pfam PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain IPR040686 Phosphoribosylaminoimidazole carboxylase, C-terminal domain 298 349 1.7E-12
Pfam PF02222 ATP-grasp domain IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type 106 272 1.0E-57
FunFam G3DSA:3.30.470.20:FF:000029 N5-carboxyaminoimidazole ribonucleotide synthase - - 176 359 1.4E-71
FunFam G3DSA:3.30.1490.20:FF:000015 N5-carboxyaminoimidazole ribonucleotide synthase - - 102 175 1.7E-31

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.