Pseudomonas aeruginosa PA7, PSPA7_1420 (ttsS )

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 24748613 Reviewed by curator
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 956 1070 2.41073E-40
Gene3D G3DSA:3.30.450.20 PAS domain - - 558 698 2.2E-12
Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF 308 508 1.2E-18
CDD cd13707 PBP2_BvgS_D2 - - 302 507 4.86519E-61
Gene3D G3DSA:3.40.190.10 - - - 294 507 9.5E-36
SMART SM00062 AABind_6 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF 63 274 1.7E-4
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 818 931 7.8E-25
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 710 764 9.17798E-11
FunFam G3DSA:3.30.565.10:FF:000010 Sensor histidine kinase RcsC - - 769 934 8.8E-45
CDD cd13705 PBP2_BvgS_D1 - - 59 276 1.31335E-64
Gene3D G3DSA:3.40.190.10 - - - 388 479 9.5E-36
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 709 770 4.4E-16
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 954 1076 3.27E-31
Pfam PF08448 PAS fold IPR013656 PAS fold-4 580 690 1.5E-7
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 893 911 9.3E-9
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1088 1192 7.1E-8
Gene3D G3DSA:3.40.190.10 - - - 145 238 6.8E-39
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 954 1070 4.6E-26
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 559 687 2.44E-13
Gene3D G3DSA:3.40.190.10 - - - 61 275 6.8E-39
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 858 872 9.3E-9
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1053 1168 1.16E-10
Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF 79 266 4.7E-18
CDD cd00130 PAS IPR000014 PAS domain 583 686 0.00121401
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 956 1070 1.5E-19
SUPERFAMILY SSF53850 Periplasmic binding protein-like II - - 296 509 1.34E-27
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 692 772 4.32E-16
SMART SM00062 AABind_6 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF 303 515 6.3E-6
Gene3D G3DSA:3.40.50.2300 - - - 946 1077 8.7E-32
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 709 770 2.9E-14
SMART SM00091 pas_2 IPR000014 PAS domain 574 642 0.0084
Coils Coil Coil - - 689 709 -
Gene3D G3DSA:1.10.287.130 - - - 699 770 8.0E-17
SUPERFAMILY SSF53850 Periplasmic binding protein-like II - - 61 276 7.06E-22
CDD cd16922 HATPase_EvgS-ArcB-TorS-like - - 822 922 1.48578E-44
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 817 935 6.8E-33
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 760 929 7.2E-41
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 771 934 1.5E-44
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 917 930 9.3E-9
PANTHER PTHR43047 TWO-COMPONENT HISTIDINE PROTEIN KINASE - - 387 1078 1.1E-123

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.