Pseudomonas aeruginosa PA7, PSPA7_1421 (ttsR )

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000156 phosphorelay response regulator activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 24748613 Reviewed by curator
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF46894
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00196
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PA7 genes in this class
Two-component regulatory systems Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 5 120 3.9E-21
SMART SM00421 luxrmega5 IPR000792 Transcription regulator LuxR, C-terminal 150 207 4.4E-13
PRINTS PR00038 LuxR bacterial regulatory protein HTH signature IPR000792 Transcription regulator LuxR, C-terminal 183 195 2.3E-7
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1 125 5.83E-23
SUPERFAMILY SSF46894 C-terminal effector domain of the bipartite response regulators IPR016032 Signal transduction response regulator, C-terminal effector 144 212 3.74E-17
PRINTS PR00038 LuxR bacterial regulatory protein HTH signature IPR000792 Transcription regulator LuxR, C-terminal 167 183 2.3E-7
Gene3D G3DSA:3.40.50.2300 - - - 1 138 3.7E-27
PRINTS PR00038 LuxR bacterial regulatory protein HTH signature IPR000792 Transcription regulator LuxR, C-terminal 153 167 2.3E-7
CDD cd06170 LuxR_C_like IPR000792 Transcription regulator LuxR, C-terminal 153 209 2.55199E-12
CDD cd17535 REC_NarL-like - - 5 121 7.25324E-35
PANTHER PTHR43214 TWO-COMPONENT RESPONSE REGULATOR IPR039420 Transcriptional regulatory protein WalR-like 2 212 6.7E-36
Pfam PF00196 Bacterial regulatory proteins, luxR family IPR000792 Transcription regulator LuxR, C-terminal 153 204 4.1E-9
Gene3D G3DSA:1.10.10.10 - IPR036388 Winged helix-like DNA-binding domain superfamily 144 213 7.7E-15
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 3 119 1.1E-14

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.