Pseudomonas aeruginosa PAO1, PA5161 (rmlB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0019305	dTDP-rhamnose biosynthetic process	ISS Inferred from Sequence or Structural Similarity Term mapped from: UniProtKB:P37759	ECO:0000250 sequence similarity evidence used in manual assertion	11065359	Reviewed by curator
Molecular Function	GO:0008460	dTDP-glucose 4,6-dehydratase activity	ISS Inferred from Sequence or Structural Similarity Term mapped from: UniProtKB:P37759	ECO:0000250 sequence similarity evidence used in manual assertion	11065359	Reviewed by curator
Biological Process	GO:0009243	O antigen biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	9023210	Reviewed by curator
Molecular Function	GO:0008460	dTDP-glucose 4,6-dehydratase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	7559340	Reviewed by curator
Biological Process	GO:0019305	dTDP-rhamnose biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	10455186	Reviewed by curator
Biological Process	GO:0044248	cellular catabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Cellular Component	GO:0009276	Gram-negative-bacterium-type cell wall	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0009244	lipopolysaccharide core region biosynthetic process	ISS Inferred from Sequence or Structural Similarity Term mapped from: UniProtKB:P37759	ECO:0000250 sequence similarity evidence used in manual assertion	11065359	Reviewed by curator
Biological Process	GO:0015976	carbon utilization	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0008460	dTDP-glucose 4,6-dehydratase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd05246	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0009225	nucleotide-sugar metabolic process	ISM Inferred from Sequence Model Term mapped from: InterPro:cd05246	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae00523	Polyketide sugar unit biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	OANTIGEN-PWY	O-antigen building blocks biosynthesis (E. coli)	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	DTDPRHAMSYN-PWY	dTDP-L-rhamnose biosynthesis I	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00525	Acarbose and validamycin biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Lipopolysaccharide biosynthesis		ECO:0000037 not_recorded
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Nucleotide sugars metabolism		ECO:0000037 not_recorded
KEGG	pae00521	Streptomycin biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
NCBIfam	TIGR01181	JCVI: dTDP-glucose 4,6-dehydratase	IPR005888	dTDP-glucose 4,6-dehydratase	3	337	0.0
PANTHER	PTHR43000	DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED	-	-	2	343	2.2E-108
Gene3D	G3DSA:3.90.25.10	-	-	-	200	332	0.0
CDD	cd05246	dTDP_GD_SDR_e	IPR005888	dTDP-glucose 4,6-dehydratase	1	333	0.0
Gene3D	G3DSA:3.40.50.720	-	-	-	3	322	0.0
SUPERFAMILY	SSF51735	NAD(P)-binding Rossmann-fold domains	IPR036291	NAD(P)-binding domain superfamily	1	335	9.26E-90
Pfam	PF16363	GDP-mannose 4,6 dehydratase	IPR016040	NAD(P)-binding domain	4	324	7.3E-102

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.