Pseudomonas aeruginosa PAO1, PA0195.1 (pntAB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0195.1
Name
pntAB
Replicon chromosome
Genomic location 225295 - 225603 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248886.2
GI 119167455
Entrez 878346
INSDC ABG56539.1
NCBI Locus Tag PA0195.1
UniParc UPI0000396C8D
UniProtKB Acc Q14T73
UniProtKB ID Q14T73_PSEAE
UniRef100 UniRef100_W0YL55
UniRef50 UniRef50_Q8XRA8
UniRef90 UniRef90_W0YL55

Product

Feature Type CDS
Coding Frame 1
Product Name
putative NAD(P) transhydrogenase, subunit alpha part 2
Product Name Confidence: Class 2
Evidence for Translation
Charge (pH 7) 4.70
Kyte-Doolittle Hydrophobicity Value 1.021
Molecular Weight (kDa) 10.7
Isoelectric Point (pI) 10.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 301 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000194 (561 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0195.1
Search term: pntAB

Human Homologs

Ensembl 86, assembly GRCh38.p7
nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]
E-value: 1.1e-17
Percent Identity: 53.0

Transposon Insertions in PAO1

Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Mutant ID UBC: PAO1_lux_51_C4
Genomic Position 225385
Position in ORF 91(309)
Reference 15805499
Type ISphoA/hah insertion site
Mutant ID UWGC: 33052
Genomic Position 225511
Position in ORF 217(309)
Reference 14617778
Type mini-Tn5 lux transposon insertion site (Non-transcriptional fusion)
Mutant ID UBC: PAO1_lux_73_D12
Genomic Position 225380
Position in ORF 86(309)
Reference 15805499
Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Mutant ID UBC: PAO1_lux_83_C10
Genomic Position 225385
Position in ORF 91(309)
Reference 15805499

Transposon Insertions in Orthologs

Type MAR2xT7 transposon (wild type background) insertion site
Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag PA14_02460
Mutant ID PA14NR: 48429
Genomic Position 222085
Position in ORF 55(309)
Reference 16477005

References

No references are associated with this feature.