Pseudomonas aeruginosa PAO1, PA0286 (desA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0286
Name
desA
Synonym: desA
Replicon chromosome
Genomic location 320766 - 321944 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_248977.1
GI 15595483
Affymetrix PA0286_at
Entrez 879596
GenBank AAG03675.1
INSDC AAG03675.1
NCBI Locus Tag PA0286
protein_id(GenBank) gb|AAG03675.1|AE004466_9|gnl|PseudoCAP|PA0286
TIGR NTL03PA00287
UniParc UPI00000C4FE2
UniProtKB Acc Q9I6K4
UniProtKB ID Q9I6K4_PSEAE
UniRef100 UniRef100_Q9I6K4
UniRef50 UniRef50_A0A069Q3K0
UniRef90 UniRef90_Q9I6K4

Product

Feature Type CDS
Coding Frame 1
Product Name
delta-9 fatty acid desaturase, DesA
Product Name Confidence: Class 1
Synonyms delta-9 fatty acid desaturase, DesA
Evidence for Translation
Charge (pH 7) 18.19
Kyte-Doolittle Hydrophobicity Value -0.053
Molecular Weight (kDa) 44.9
Isoelectric Point (pI) 10.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 181 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000283 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0286
Search term: desA

Human Homologs

References

Two aerobic pathways for the formation of unsaturated fatty acids in Pseudomonas aeruginosa.
Zhu K, Choi KH, Schweizer HP, Rock CO, Zhang YM
Mol Microbiol 2006 Apr;60(2):260-73
PubMed ID: 16573679