Pseudomonas aeruginosa PAO1, PA0365 (laoB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0365
Name
laoB
Replicon chromosome
Genomic location 408901 - 409449 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentPart of the Lao (long-chain-alcohol/aldehyde-oxidation) gene cluster (laoABC).

Cross-References

RefSeq NP_249056.1
GI 15595562
Affymetrix PA0365_at
DNASU PaCD00006157
Entrez 879873
GenBank AAG03754.1
INSDC AAG03754.1
NCBI Locus Tag PA0365
protein_id(GenBank) gb|AAG03754.1|AE004474_6|gnl|PseudoCAP|PA0365
TIGR NTL03PA00366
UniParc UPI00000C502A
UniProtKB Acc Q9I6C9
UniProtKB ID Q9I6C9_PSEAE
UniRef100 UniRef100_W0YLJ7
UniRef50 UniRef50_J3ER45
UniRef90 UniRef90_A6UYG9

Product

Feature Type CDS
Coding Frame 1
Product Name
LaoB
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 0.65
Kyte-Doolittle Hydrophobicity Value 0.135
Molecular Weight (kDa) 19.6
Isoelectric Point (pI) 7.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 15 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000356 (485 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0365
Search term: laoB
Search term: LaoB

Human Homologs

References

LaoABCR, a Novel System for Oxidation of Long-Chain Alcohols Derived from SDS and Alkane Degradation in Pseudomonas aeruginosa.
Panasia G, Philipp B
Appl Environ Microbiol 2018 Jul 1;84(13)
PubMed ID: 29678916