Pseudomonas aeruginosa PAO1, PA0412 (pilK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0412
Name
pilK
Replicon chromosome
Genomic location 453239 - 454114 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249103.1
GI 15595609
Affymetrix PA0412_pilK_at
DNASU PaCD00006177
Entrez 878179
GenBank AAG03801.1
INSDC AAG03801.1
NCBI Locus Tag PA0412
protein_id(GenBank) gb|AAG03801.1|AE004478_6|gnl|PseudoCAP|PA0412
TIGR NTL03PA00413
UniParc UPI00000D420F
UniProtKB Acc G3XCT5
UniProtKB ID G3XCT5_PSEAE
UniRef100 UniRef100_W0YN07
UniRef50 UniRef50_W6QQY4
UniRef90 UniRef90_Q02U00

Product

Feature Type CDS
Coding Frame 1
Product Name
methyltransferase PilK
Product Name Confidence: Class 1
Synonyms type 4 fimbrial biogenesis protein PilK
Evidence for Translation
Charge (pH 7) 1.79
Kyte-Doolittle Hydrophobicity Value -0.322
Molecular Weight (kDa) 33.3
Isoelectric Point (pI) 7.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0082
Category Type IV pili twitching motility related proteins
Evidence
Host Organism
Notes
Reference 9224879

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 412 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000403 (885 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0412
Search term: pilK

References

The Pseudomonas aeruginosa pilK gene encodes a chemotactic methyltransferase (CheR) homologue that is translationally regulated.
Darzins A
Mol. Microbiol. 1995 Feb;15(4):703-17
PubMed ID: 7783642
The molecular genetics of type-4 fimbriae in Pseudomonas aeruginosa--a review.
Mattick JS, Whitchurch CB, Alm RA
Gene 1996 Nov;179(1):147-55
PubMed ID: 8955641