Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0962
|
Name |
dps
|
Replicon | chromosome |
Genomic location | 1047549 - 1048019 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Dps Protects P. aeruginosa cells from H2O2-mediated oxidative stress (PMID:36902100) |
RefSeq | NP_249653.1 |
GI | 15596159 |
Affymetrix | PA0962_at |
Entrez | 881882 |
GenBank | AAG04351.1 |
INSDC | AAG04351.1 |
NCBI Locus Tag | PA0962 |
protein_id(GenBank) | gb|AAG04351.1|AE004530_4|gnl|PseudoCAP|PA0962 |
TIGR | NTL03PA00963 |
UniParc | UPI00000C51E1 |
UniProtKB Acc | Q9I4Z7 |
UniProtKB ID | Q9I4Z7_PSEAE |
UniRef100 | UniRef100_W0YMY0 |
UniRef50 | UniRef50_Q2L0H0 |
UniRef90 | UniRef90_L8MEK7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
DNA-binding protein from starved cells, Dps
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Verified using two-dimensional gel electrophoresis, MALDI-TOF MS and peptide mass mapping(pI:5.0, molecular weight:17.5, PMID:21674802)
|
Charge (pH 7) | -7.04 |
Kyte-Doolittle Hydrophobicity Value | -0.123 |
Molecular Weight (kDa) | 17.5 |
Isoelectric Point (pI) | 4.70 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
8FF9 | METAL BINDING PROTEIN | 12/08/22 | Crystal structure of Apo Dps protein (PA0962) from Pseudomonas aeruginosa (orthorhombic form) | Pseudomonas aeruginosa | 1.7 | X-RAY DIFFRACTION | 100.0 |
8FFA | METAL BINDING PROTEIN | 12/08/22 | Crystal structure of Apo Dps protein (PA0962) from Pseudomonas aeruginosa (cubic form) | Pseudomonas aeruginosa PAO1 | 2.15 | X-RAY DIFFRACTION | 100.0 |
8FFB | METAL BINDING PROTEIN | 12/08/22 | Crystal structure of iron bound Dps protein (PA0962) from Pseudomonas aeruginosa (orthorhombic form) | Pseudomonas aeruginosa PAO1 | 2.25 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 381 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000927 (509 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0962
Search term: dps
Search term: DNA-binding protein from starved cells, Dps
|
Metalloregulation in Bacillus subtilis: isolation and characterization of two genes differentially repressed by metal ions.
Chen L, James LP, Helmann JD
J Bacteriol 1993 Sep;175(17):5428-37
PubMed ID: 8396117
|
First steps from a two-dimensional protein index towards a response-regulation map for Bacillus subtilis.
Antelmann H, Bernhardt J, Schmid R, Mach H, Völker U, Hecker M
Electrophoresis 1997 Aug;18(8):1451-63
PubMed ID: 9298659
|
Proteomics of the oxidative stress response induced by hydrogen peroxide and paraquat reveals a novel AhpC-like protein in Pseudomonas aeruginosa.
Hare NJ, Scott NE, Shin EH, Connolly AM, Larsen MR, Palmisano G, Cordwell SJ
Proteomics 2011 Aug;11(15):3056-69
PubMed ID: 21674802
|
A proteome analysis of the response of a Pseudomonas aeruginosa oxyR mutant to iron limitation.
Vinckx T, Wei Q, Matthijs S, Noben JP, Daniels R, Cornelis P
Biometals 2011 Jun;24(3):523-32
PubMed ID: 21207115
|
Pseudomonas aeruginosa Dps (PA0962) Functions in H(2)O(2) Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity.
Rajapaksha N, Soldano A, Yao H, Donnarumma F, Kashipathy MM, Seibold S, Battaile KP, Lovell S, Rivera M
Int J Mol Sci 2023 Feb 28;24(5)
PubMed ID: 36902100
|