Pseudomonas aeruginosa UCBPP-PA14, PA14_19050 (metG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_19050
Name
metG
Replicon chromosome
Genomic location 1644279 - 1646315 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_789665.1
GI 116051500
EC Number 6.1.1.10
Entrez 4381466
INSDC ABJ12736.1
NCBI Locus Tag PA14_19050
UniParc UPI00003960C8
UniProtKB Acc Q02QX1
UniProtKB ID SYM_PSEAB
UniRef100 UniRef100_Q02QX1
UniRef50 UniRef50_Q9HYC7
UniRef90 UniRef90_Q9HYC7

Product

Feature Type CDS
Coding Frame 1
Product Name
methionyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -13.63
Kyte-Doolittle Hydrophobicity Value -0.191
Molecular Weight (kDa) 75.0
Isoelectric Point (pI) 5.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7ULZ LIGASE 04/05/22 Crystal Structure of Methionine-tRNA ligase / Methionyl-tRNA synthetase (MetRS) from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa 2.8 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002160 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_19050
Search term: metG

Human Homologs

Ensembl 110, assembly GRCh38.p14
methionyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25133]
E-value: 6.8e-36
Percent Identity: 25.4

References

No references are associated with this feature.