Pseudomonas aeruginosa PAO1, PA2470 (gtdA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2470
Name
gtdA
Replicon chromosome
Genomic location 2788011 - 2789072 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251160.1
GI 15597666
Affymetrix PA2470_gtdA_at
Entrez 882920
GenBank AAG05858.1
INSDC AAG05858.1
NCBI Locus Tag PA2470
protein_id(GenBank) gb|AAG05858.1|AE004674_8|gnl|PseudoCAP|PA2470
TIGR NTL03PA02470
UniParc UPI00000C56EF
UniProtKB Acc Q9I112
UniProtKB ID Q9I112_PSEAE
UniRef100 UniRef100_Q9I112
UniRef50 UniRef50_Q2L0Y7
UniRef90 UniRef90_A6V4Z3

Product

Feature Type CDS
Coding Frame 1
Product Name
gentisate 1,2-dioxygenase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.44
Kyte-Doolittle Hydrophobicity Value -0.331
Molecular Weight (kDa) 39.3
Isoelectric Point (pI) 6.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 79 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003082 (306 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2470
Search term: gtdA

Human Homologs

References

Biochemical and genetic characterization of a gentisate 1, 2-dioxygenase from Sphingomonas sp. strain RW5.
Werwath J, Arfmann HA, Pieper DH, Timmis KN, Wittich RM
J Bacteriol 1998 Aug;180(16):4171-6
PubMed ID: 9696766