Pseudomonas aeruginosa PAO1, PA2472

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2472
Name
Replicon chromosome
Genomic location 2789861 - 2791207 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251162.1
GI 15597668
Affymetrix PA2472_at
Entrez 882916
GenBank AAG05860.1
INSDC AAG05860.1
NCBI Locus Tag PA2472
protein_id(GenBank) gb|AAG05860.1|AE004675_1|gnl|PseudoCAP|PA2472
TIGR NTL03PA02472
UniParc UPI00000C56F1
UniProtKB Acc Q9I110
UniProtKB ID Q9I110_PSEAE
UniRef100 UniRef100_S0IKB1
UniRef50 UniRef50_Q8Y0F1
UniRef90 UniRef90_W0WF77

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 10.01
Kyte-Doolittle Hydrophobicity Value 0.734
Molecular Weight (kDa) 46.6
Isoelectric Point (pI) 9.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 401 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003080 (299 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2472

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 22 member 6 [Source:HGNC Symbol;Acc:HGNC:10970]
E-value: 4.1e-05
Percent Identity: 27.0
Ensembl 110, assembly GRCh38.p14
solute carrier family 22 member 6 [Source:HGNC Symbol;Acc:HGNC:10970]
E-value: 4.1e-05
Percent Identity: 27.0

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Identification of the pcaRKF gene cluster from Pseudomonas putida: involvement in chemotaxis, biodegradation, and transport of 4-hydroxybenzoate.
Harwood CS, Nichols NN, Kim MK, Ditty JL, Parales RE
J Bacteriol 1994 Nov;176(21):6479-88
PubMed ID: 7961399