Pseudomonas aeruginosa PAO1, PA2475

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2475
Name
Replicon chromosome
Genomic location 2792799 - 2794133 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_251165.1
GI 15597671
Affymetrix PA2475_at
Entrez 879833
GenBank AAG05863.1
INSDC AAG05863.1
NCBI Locus Tag PA2475
protein_id(GenBank) gb|AAG05863.1|AE004675_4|gnl|PseudoCAP|PA2475
TIGR NTL03PA02475
UniParc UPI00000C60AC
UniProtKB Acc Q9I107
UniProtKB ID Q9I107_PSEAE
UniRef100 UniRef100_Q9I107
UniRef50 UniRef50_Q9I107
UniRef90 UniRef90_Q9I107

Product

Feature Type CDS
Coding Frame 1
Product Name
probable cytochrome P450
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.78
Kyte-Doolittle Hydrophobicity Value -0.249
Molecular Weight (kDa) 49.4
Isoelectric Point (pI) 6.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 195 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001998 (906 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2475

Human Homologs

References

Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase.
Andersen JF, Hutchinson CR
J Bacteriol 1992 Feb;174(3):725-35
PubMed ID: 1732208