Pseudomonas aeruginosa PAO1, PA2512 (antA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2512
Name
antA
Replicon chromosome
Genomic location 2829440 - 2830834 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_251202.1
GI 15597708
Affymetrix PA2512_antA_at
Entrez 882892
GenBank AAG05900.1
INSDC AAG05900.1
NCBI Locus Tag PA2512
protein_id(GenBank) gb|AAG05900.1|AE004678_6|gnl|PseudoCAP|PA2512
TIGR NTL03PA02512
UniParc UPI00000CAC6D
UniProtKB Acc Q9I0X0
UniProtKB ID Q9I0X0_PSEAE
UniRef100 UniRef100_Q9I0X0
UniRef50 UniRef50_O85673
UniRef90 UniRef90_A6V4V0

Product

Feature Type CDS
Coding Frame 1
Product Name
anthranilate dioxygenase large subunit
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -5.79
Kyte-Doolittle Hydrophobicity Value -0.414
Molecular Weight (kDa) 52.5
Isoelectric Point (pI) 6.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 204 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003046 (1308 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2512
Search term: antA

Human Homologs

References

Similarities between the antABC-encoded anthranilate dioxygenase and the benABC-encoded benzoate dioxygenase of Acinetobacter sp. strain ADP1.
Bundy BM, Campbell AL, Neidle EL
J Bacteriol 1998 Sep;180(17):4466-74
PubMed ID: 9721284