Pseudomonas aeruginosa PAO1, PA2574 (alkB1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2574
Name
alkB1
Replicon chromosome
Genomic location 2910729 - 2911877 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251264.1
GI 15597770
Affymetrix PA2574_at
Entrez 878705
GenBank AAG05962.1
INSDC AAG05962.1
NCBI Locus Tag PA2574
protein_id(GenBank) gb|AAG05962.1|AE004685_8|gnl|PseudoCAP|PA2574
TIGR NTL03PA02574
UniParc UPI00000C5748
UniProtKB Acc Q9I0R2
UniProtKB ID ALKB1_PSEAE
UniRef100 UniRef100_Q9I0R2
UniRef50 UniRef50_Q0VTH3
UniRef90 UniRef90_Q9I0R2

Product

Feature Type CDS
Coding Frame 1
Product Name
alkane-1-monooxygenase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.04
Kyte-Doolittle Hydrophobicity Value 0.177
Molecular Weight (kDa) 43.3
Isoelectric Point (pI) 7.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 68 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002971 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2574
Search term: alkB1

Human Homologs

References

Functional analysis of alkane hydroxylases from gram-negative and gram-positive bacteria.
Smits TH, Balada SB, Witholt B, van Beilen JB
J Bacteriol 2002 Mar;184(6):1733-42
PubMed ID: 11872725
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295