Pseudomonas aeruginosa PAO1, PA2577

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2577
Name
Replicon chromosome
Genomic location 2913922 - 2914359 (+ strand)

Cross-References

RefSeq NP_251267.1
GI 15597773
Affymetrix PA2577_at
Entrez 880008
GenBank AAG05965.1
INSDC AAG05965.1
NCBI Locus Tag PA2577
protein_id(GenBank) gb|AAG05965.1|AE004686_3|gnl|PseudoCAP|PA2577
TIGR NTL03PA02577
UniParc UPI00000C574B
UniProtKB Acc Q9I0Q9
UniProtKB ID Q9I0Q9_PSEAE
UniRef100 UniRef100_W0YQN0
UniRef50 UniRef50_I3X429
UniRef90 UniRef90_W0YQN0

Product

Feature Type CDS
Coding Frame 1
Product Name
Lrp/AsnC transcriptional regulator
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.14
Kyte-Doolittle Hydrophobicity Value -0.316
Molecular Weight (kDa) 16.5
Isoelectric Point (pI) 8.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 432 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002968 (890 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2577

Human Homologs

References

The Lrp/AsnC-Type Regulator PA2577 Controls the EamA-like Transporter Gene PA2576 in Pseudomonas aeruginosa.
Modrzejewska M, Kawalek A, Bartosik AA
Int J Mol Sci 2021 Dec 12;22(24)
PubMed ID: 34948137