Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2579
|
Name |
kynA
|
Replicon | chromosome |
Genomic location | 2914966 - 2915832 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Genetic evidence. |
RefSeq | NP_251269.1 |
GI | 15597775 |
Affymetrix | PA2579_at |
DNASU | PaCD00007113 |
Entrez | 879140 |
GenBank | AAG05967.1 |
INSDC | AAG05967.1 |
NCBI Locus Tag | PA2579 |
protein_id(GenBank) | gb|AAG05967.1|AE004686_5|gnl|PseudoCAP|PA2579 |
TIGR | NTL03PA02579 |
UniParc | UPI00000C574D |
UniProtKB Acc | Q9I0Q7 |
UniProtKB ID | T23O_PSEAE |
UniRef100 | UniRef100_Q9I0Q7 |
UniRef50 | UniRef50_Q1LK00 |
UniRef90 | UniRef90_Q9I0Q7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing) KynA
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -3.21 |
Kyte-Doolittle Hydrophobicity Value | -0.310 |
Molecular Weight (kDa) | 32.9 |
Isoelectric Point (pI) | 6.51 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 136 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002967 (352 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2579
Search term: kynA
|
Ensembl
110, assembly
GRCh38.p14
|
tryptophan 2,3-dioxygenase [Source:HGNC Symbol;Acc:HGNC:11708]
E-value:
3.3e-16
Percent Identity:
43.2
|
Ensembl
110, assembly
GRCh38.p14
|
tryptophan 2,3-dioxygenase [Source:HGNC Symbol;Acc:HGNC:11708]
E-value:
3.3e-16
Percent Identity:
43.2
|
Two distinct pathways supply anthranilate as a precursor of the Pseudomonas quinolone signal.
Farrow JM 3rd, Pesci EC
J Bacteriol 2007 May;189(9):3425-33
PubMed ID: 17337571
|
Aerobic tryptophan degradation pathway in bacteria: novel kynurenine formamidase.
Kurnasov O, Jablonski L, Polanuyer B, Dorrestein P, Begley T, Osterman A
FEMS Microbiol Lett 2003 Oct 24;227(2):219-27
PubMed ID: 14592712
|