Pseudomonas aeruginosa PAO1, PA2738 (himA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2738
Name
himA
Replicon chromosome
Genomic location 3099810 - 3100112 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_251428.1
GI 15597934
Affymetrix PA2738_himA_at
DNASU PaCD00007184
Entrez 882954
GenBank AAG06126.1
INSDC AAG06126.1
NCBI Locus Tag PA2738
protein_id(GenBank) gb|AAG06126.1|AE004702_3|gnl|PseudoCAP|PA2738
TIGR NTL03PA02738
UniParc UPI000012D438
UniProtKB Acc Q51472
UniProtKB ID IHFA_PSEAE
UniRef100 UniRef100_A6V491
UniRef50 UniRef50_P37982
UniRef90 UniRef90_A6V491

Product

Feature Type CDS
Coding Frame 1
Product Name
integration host factor, alpha subunit
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.23
Kyte-Doolittle Hydrophobicity Value -0.800
Molecular Weight (kDa) 11.5
Isoelectric Point (pI) 10.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 560 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002833 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2738
Search term: himA

Human Homologs

References

Pseudomonas aeruginosa contains an IHF-like protein that binds to the algD promoter.
Toussaint B, Delic-Attree I, Vignais PM
Biochem Biophys Res Commun 1993 Oct 15;196(1):416-421
PubMed ID: 8216322
Cloning and sequence analyses of the genes coding for the integration host factor (IHF) and HU proteins of Pseudomonas aeruginosa.
Delic-Attree I, Toussaint B, Vignais PM
Gene 1995 Feb 27;154(1):61-4
PubMed ID: 7867950