Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2755
|
Name |
eco
|
Replicon | chromosome |
Genomic location | 3116654 - 3117124 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment |
RefSeq | NP_251445.1 |
GI | 15597951 |
Affymetrix | PA2755_eco_at |
DNASU | PaCD00007195 |
Entrez | 882725 |
GenBank | AAG06143.1 |
INSDC | AAG06143.1 |
NCBI Locus Tag | PA2755 |
protein_id(GenBank) | gb|AAG06143.1|AE004703_9|gnl|PseudoCAP|PA2755 |
TIGR | NTL03PA02755 |
UniParc | UPI0000129B88 |
UniProtKB Acc | Q9I088 |
UniProtKB ID | ECOT_PSEAE |
UniRef100 | UniRef100_Q9I088 |
UniRef50 | UniRef50_Q9I088 |
UniRef90 | UniRef90_Q9I088 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
ecotin precursor
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by two-dimensional gel electrophoresis and mass spectral analysis(PMID:21863142).
Detected by MALDI-TOF/TOF (PMID:19333994).
|
Charge (pH 7) | -0.62 |
Kyte-Doolittle Hydrophobicity Value | -0.206 |
Molecular Weight (kDa) | 17.2 |
Isoelectric Point (pI) | 6.52 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 38 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002813 (409 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2755
Search term: eco
Search term: ecotin precursor
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
The sequence and reactive site of ecotin. A general inhibitor of pancreatic serine proteases from Escherichia coli.
McGrath ME, Hines WM, Sakanari JA, Fletterick RJ, Craik CS
J Biol Chem 1991 Apr 5;266(10):6620-5
PubMed ID: 2007606
|
Ecotin: lessons on survival in a protease-filled world.
McGrath ME, Gillmor SA, Fletterick RJ
Protein Sci 1995 Feb;4(2):141-8
PubMed ID: 7757004
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142
|
A Biofilm Matrix-Associated Protease Inhibitor Protects Pseudomonas aeruginosa from Proteolytic Attack.
Tseng BS, Reichhardt C, Merrihew GE, Araujo-Hernandez SA, Harrison JJ, MacCoss MJ, Parsek MR
mBio 2018 Apr 10;9(2)
PubMed ID: 29636440
|