Pseudomonas aeruginosa PAO1, PA2787 (cpg2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2787
Name
cpg2
Replicon chromosome
Genomic location 3143152 - 3144390 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251477.1
GI 15597983
Affymetrix PA2787_cpg2_at
Entrez 882782
GenBank AAG06175.1
INSDC AAG06175.1
NCBI Locus Tag PA2787
protein_id(GenBank) gb|AAG06175.1|AE004706_5|gnl|PseudoCAP|PA2787
TIGR NTL03PA02787
UniParc UPI00000C5807
UniProtKB Acc Q9I056
UniProtKB ID Q9I056_PSEAE
UniRef100 UniRef100_Q9I056
UniRef50 UniRef50_A0A077JZ89
UniRef90 UniRef90_A0A077JZ89

Product

Feature Type CDS
Coding Frame 1
Product Name
carboxypeptidase G2 precursor
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -3.54
Kyte-Doolittle Hydrophobicity Value -0.170
Molecular Weight (kDa) 44.0
Isoelectric Point (pI) 6.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 387 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002782 (424 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2787
Search term: cpg2

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Purification and properties of carboxypeptidase G2 from Pseudomonas sp. strain RS-16. Use of a novel triazine dye affinity method.
Sherwood RF, Melton RG, Alwan SM, Hughes P
Eur J Biochem 1985 May 2;148(3):447-53
PubMed ID: 3838935
Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy.
Rowsell S, Pauptit RA, Tucker AD, Melton RG, Blow DM, Brick P
Structure 1997 Mar 15;5(3):337-47
PubMed ID: 9083113