Pseudomonas aeruginosa PAO1, PA2828

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2828
Name
Replicon chromosome
Genomic location 3181137 - 3182348 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251518.1
GI 15598024
Affymetrix PA2828_at
Entrez 878850
GenBank AAG06216.1
INSDC AAG06216.1
NCBI Locus Tag PA2828
protein_id(GenBank) gb|AAG06216.1|AE004709_9|gnl|PseudoCAP|PA2828
TIGR NTL03PA02828
UniParc UPI00000C582D
UniProtKB Acc Q9I015
UniProtKB ID Q9I015_PSEAE
UniRef100 UniRef100_W0YUF7
UniRef50 UniRef50_P0A960
UniRef90 UniRef90_E2XNW2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable aminotransferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.26
Kyte-Doolittle Hydrophobicity Value -0.096
Molecular Weight (kDa) 44.8
Isoelectric Point (pI) 6.11

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 654 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002739 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2828

Human Homologs

Ensembl 110, assembly GRCh38.p14
tyrosine aminotransferase [Source:HGNC Symbol;Acc:HGNC:11573]
E-value: 2.5e-33
Percent Identity: 28.2

References

Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994