Pseudomonas aeruginosa PAO1, PA2861 (ligT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2861
Name
ligT
Replicon chromosome
Genomic location 3213538 - 3214086 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251551.1
GI 15598057
Affymetrix PA2861_ligT_at
DNASU PaCD00007247
Entrez 882606
GenBank AAG06249.1
INSDC AAG06249.1
NCBI Locus Tag PA2861
protein_id(GenBank) gb|AAG06249.1|AE004712_9|gnl|PseudoCAP|PA2861
TIGR NTL03PA02861
UniParc UPI00000C584B
UniProtKB Acc Q9HZY3
UniProtKB ID Q9HZY3_PSEAE
UniRef100 UniRef100_Q9HZY3
UniRef50 UniRef50_Q9HZY3
UniRef90 UniRef90_Q9HZY3

Product

Feature Type CDS
Coding Frame 1
Product Name
2'-5' RNA ligase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 2.62
Kyte-Doolittle Hydrophobicity Value -0.077
Molecular Weight (kDa) 20.4
Isoelectric Point (pI) 8.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 121 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002708 (344 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2861
Search term: ligT
Search term: 2'-5' RNA ligase

Human Homologs

References

The 2'-5' RNA ligase of Escherichia coli. Purification, cloning, and genomic disruption.
Arn EA, Abelson JN
J Biol Chem 1996 Dec 6;271(49):31145-53
PubMed ID: 8940112