Pseudomonas aeruginosa PAO1, PA2890 (atuE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2890
Name
atuE
Replicon chromosome
Genomic location 3243505 - 3244299 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251580.1
GI 15598086
Affymetrix PA2890_at
DNASU PaCD00007264
Entrez 882708
GenBank AAG06278.1
INSDC AAG06278.1
NCBI Locus Tag PA2890
protein_id(GenBank) gb|AAG06278.1|AE004715_4|gnl|PseudoCAP|PA2890
TIGR NTL03PA02890
UniParc UPI00000C5865
UniProtKB Acc Q9HZV7
UniProtKB ID Q9HZV7_PSEAE
UniRef100 UniRef100_Q9HZV7
UniRef50 UniRef50_I0HUE1
UniRef90 UniRef90_Q9HZV7

Product

Feature Type CDS
Coding Frame 1
Product Name
putative isohexenylglutaconyl-CoA hydratase
Product Name Confidence: Class 3
Synonyms gamma-carboxygeranyl-CoA hydratase
Evidence for Translation
Charge (pH 7) -4.42
Kyte-Doolittle Hydrophobicity Value 0.185
Molecular Weight (kDa) 27.7
Isoelectric Point (pI) 5.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4ZU2 HYDROLASE 05/15/15 Pseudomonas aeruginosa AtuE Pseudomonas aeruginosa 2.15 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 499 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002683 (394 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2890
Search term: atuE

Human Homologs

Ensembl 110, assembly GRCh38.p14
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247]
E-value: 2.9e-14
Percent Identity: 30.0

References

Identification of genes and proteins necessary for catabolism of acyclic terpenes and leucine/isovalerate in Pseudomonas aeruginosa.
Förster-Fromme K, Höschle B, Mack C, Bott M, Armbruster W, Jendrossek D
Appl Environ Microbiol 2006 Jul;72(7):4819-28
PubMed ID: 16820476