Pseudomonas aeruginosa PAO1, PA2953

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2953
Name
Replicon chromosome
Genomic location 3312791 - 3314446 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251643.1
GI 15598149
Affymetrix PA2953_at
Entrez 880159
GenBank AAG06341.1
INSDC AAG06341.1
NCBI Locus Tag PA2953
protein_id(GenBank) gb|AAG06341.1|AE004721_9|gnl|PseudoCAP|PA2953
TIGR NTL03PA02953
UniParc UPI00000C58A3
UniProtKB Acc Q9HZP5
UniProtKB ID ETFD_PSEAE
UniRef100 UniRef100_Q9HZP5
UniRef50 UniRef50_Q9HZP5
UniRef90 UniRef90_Q9HZP5

Product

Feature Type CDS
Coding Frame 1
Product Name
electron transfer flavoprotein-ubiquinone oxidoreductase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (59.93 kDa, PMID:21751344)
Charge (pH 7) -12.47
Kyte-Doolittle Hydrophobicity Value -0.270
Molecular Weight (kDa) 59.9
Isoelectric Point (pI) 5.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 230 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002628 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2953

Human Homologs

Ensembl 110, assembly GRCh38.p14
electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483]
E-value: 7.0e-172
Percent Identity: 54.5
Ensembl 110, assembly GRCh38.p14
electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483]
E-value: 7.0e-172
Percent Identity: 54.5
Ensembl 110, assembly GRCh38.p14
electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483]
E-value: 7.0e-172
Percent Identity: 54.5
Ensembl 110, assembly GRCh38.p14
electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483]
E-value: 7.0e-172
Percent Identity: 54.5
Ensembl 110, assembly GRCh38.p14
electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483]
E-value: 7.0e-172
Percent Identity: 54.5

References

Molecular cloning and expression of a cDNA encoding human electron transfer flavoprotein-ubiquinone oxidoreductase.
Goodman SI, Axtell KM, Bindoff LA, Beard SE, Gill RE, Frerman FE
Eur J Biochem 1994 Jan 15;219(1-2):277-86
PubMed ID: 8306995
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344