Pseudomonas aeruginosa PAO1, PA2957

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2957
Name
Replicon chromosome
Genomic location 3316800 - 3317438 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251647.1
GI 15598153
Affymetrix PA2957_at
Entrez 880200
GenBank AAG06345.1
INSDC AAG06345.1
NCBI Locus Tag PA2957
protein_id(GenBank) gb|AAG06345.1|AE004722_1|gnl|PseudoCAP|PA2957
TIGR NTL03PA02957
UniParc UPI00000C58A7
UniProtKB Acc Q9HZP1
UniProtKB ID Q9HZP1_PSEAE
UniRef100 UniRef100_W0YSW9
UniRef50 UniRef50_G8Q174
UniRef90 UniRef90_M4X208

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transcriptional regulator
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.66
Kyte-Doolittle Hydrophobicity Value -0.553
Molecular Weight (kDa) 25.0
Isoelectric Point (pI) 7.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7W2Q DNA BINDING PROTEIN 11/24/21 Crystal structure of Pseudomonas aeruginosa transcriptional regulator PvrA in the narrow conformation Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.8 X-RAY DIFFRACTION 100.0
8HJB TRANSCRIPTION 11/23/22 Crystal structure of Pseudomonas aeruginosa PvrA with coenzyme A Pseudomonas aeruginosa PA14 2.65 X-RAY DIFFRACTION 100.0
7Y0Z TRANSCRIPTION 06/06/22 Crystal structure of Pseudomonas aeruginosa PvrA Pseudomonas aeruginosa PA14 2.3 X-RAY DIFFRACTION 100.0
7Y0Y TRANSCRIPTION 06/06/22 Crystal structure of Pseudomonas aeruginosa PvrA (SeMet) Pseudomonas aeruginosa PA14 2.09 X-RAY DIFFRACTION 100.0
7W2O DNA BINDING PROTEIN 11/24/21 Crystal structure of Pseudomonas aeruginosa transcriptional regulator PvrA in the wide conformation Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.21 X-RAY DIFFRACTION 100.0
7XAQ TRANSCRIPTION 03/18/22 Cryo-EM structure of PvrA-DNA complex Pseudomonas aeruginosa PAO1 3.59 ELECTRON MICROSCOPY 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 273 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002624 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2957

Human Homologs

References

No references are associated with this feature.