Pseudomonas aeruginosa PAO1, PA2983

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2983
Name
Replicon chromosome
Genomic location 3340114 - 3340749 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_251673.1
GI 15598179
Affymetrix PA2983_at
DNASU PaCD00007303
Entrez 878711
GenBank AAG06371.1
INSDC AAG06371.1
NCBI Locus Tag PA2983
protein_id(GenBank) gb|AAG06371.1|AE004723_15|gnl|PseudoCAP|PA2983
TIGR NTL03PA02983
UniParc UPI00000C58B4
UniProtKB Acc Q9HZM1
UniProtKB ID Q9HZM1_PSEAE
UniRef100 UniRef100_W0YW37
UniRef50 UniRef50_G8Q273
UniRef90 UniRef90_B7V145

Product

Feature Type CDS
Coding Frame 1
Product Name
probable tolQ-type transport protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (22.89 kDa, PMID:21751344)
Charge (pH 7) -0.31
Kyte-Doolittle Hydrophobicity Value 0.373
Molecular Weight (kDa) 22.9
Isoelectric Point (pI) 6.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 404 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002599 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2983

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344