Pseudomonas aeruginosa PAO1, PA2995 (nqrE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2995
Name
nqrE
Replicon chromosome
Genomic location 3352890 - 3353498 (- strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251685.1
GI 15598191
Affymetrix PA2995_nqrE_at
DNASU PaCD00007308
Entrez 880456
GenBank AAG06383.1
INSDC AAG06383.1
NCBI Locus Tag PA2995
protein_id(GenBank) gb|AAG06383.1|AE004724_12|gnl|PseudoCAP|PA2995
TIGR NTL03PA02995
UniParc UPI000013045D
UniProtKB Acc Q9HZL0
UniProtKB ID NQRE_PSEAE
UniRef100 UniRef100_A6V3A1
UniRef50 UniRef50_A6V3A1
UniRef90 UniRef90_A6V3A1

Product

Feature Type CDS
Coding Frame 1
Product Name
Na+-translocating NADH:quinone oxidoreductase subunit Nqr5
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.84
Kyte-Doolittle Hydrophobicity Value 0.998
Molecular Weight (kDa) 21.7
Isoelectric Point (pI) 4.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 226 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002586 (340 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2995
Search term: nqrE

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295