Pseudomonas aeruginosa PAO1, PA2996 (nqrD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2996
Name
nqrD
Replicon chromosome
Genomic location 3353498 - 3354172 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251686.1
GI 15598192
Affymetrix PA2996_nqrD_at
Entrez 880457
GenBank AAG06384.1
INSDC AAG06384.1
NCBI Locus Tag PA2996
protein_id(GenBank) gb|AAG06384.1|AE004724_13|gnl|PseudoCAP|PA2996
TIGR NTL03PA02996
UniParc UPI0000130452
UniProtKB Acc Q9HZK9
UniProtKB ID NQRD_PSEAE
UniRef100 UniRef100_B7UZU0
UniRef50 UniRef50_Q57095
UniRef90 UniRef90_B7UZU0

Product

Feature Type CDS
Coding Frame 1
Product Name
Na+-translocating NADH:uniquinone oxidoreductase subunit Nqr4
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 5.92
Kyte-Doolittle Hydrophobicity Value 0.737
Molecular Weight (kDa) 24.3
Isoelectric Point (pI) 9.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 226 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002585 (339 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2996
Search term: nqrD

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Cloning and sequencing of four structural genes for the Na(+)-translocating NADH-ubiquinone oxidoreductase of Vibrio alginolyticus.
Beattie P, Tan K, Bourne RM, Leach D, Rich PR, Ward FB
FEBS Lett 1994 Dec 19;356(2-3):333-8
PubMed ID: 7805867