Pseudomonas aeruginosa PAO1, PA3243 (minC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3243
Name
minC
Replicon chromosome
Genomic location 3630765 - 3631556 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251933.1
GI 15598439
Affymetrix PA3243_minC_at
DNASU PaCD00007429
Entrez 882406
GenBank AAG06631.1
INSDC AAG06631.1
NCBI Locus Tag PA3243
protein_id(GenBank) gb|AAG06631.1|AE004747_4|gnl|PseudoCAP|PA3243
TIGR NTL03PA03243
UniParc UPI000012F11D
UniProtKB Acc Q9HYZ7
UniProtKB ID MINC_PSEAE
UniRef100 UniRef100_B7V7X6
UniRef50 UniRef50_Q48L73
UniRef90 UniRef90_B7V7X6

Product

Feature Type CDS
Coding Frame 1
Product Name
cell division inhibitor MinC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.09
Kyte-Doolittle Hydrophobicity Value -0.180
Molecular Weight (kDa) 28.1
Isoelectric Point (pI) 6.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6RIQ PROTEIN FIBRIL 04/24/19 MinCD filament from Pseudomonas aeruginosa Pseudomonas aeruginosa 3.1 ELECTRON MICROSCOPY 96.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 210 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002365 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3243
Search term: minC

Human Homologs

References

A division inhibitor and a topological specificity factor coded for by the minicell locus determine proper placement of the division septum in E. coli.
de Boer PA, Crossley RE, Rothfield LI
Cell 1989 Feb 24;56(4):641-9
PubMed ID: 2645057