Pseudomonas aeruginosa PAO1, PA3391 (nosR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3391
Name
nosR
Replicon chromosome
Genomic location 3794819 - 3796966 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252081.1
GI 15598587
Affymetrix PA3391_nosR_at
Entrez 879823
GenBank AAG06779.1
INSDC AAG06779.1
NCBI Locus Tag PA3391
protein_id(GenBank) gb|AAG06779.1|AE004760_7|gnl|PseudoCAP|PA3391
TIGR NTL03PA03391
UniParc UPI0000130554
UniProtKB Acc Q9HYL3
UniProtKB ID NOSR_PSEAE
UniRef100 UniRef100_Q9HYL3
UniRef50 UniRef50_Q9HYL3
UniRef90 UniRef90_Q9HYL3

Product

Feature Type CDS
Coding Frame 1
Product Name
regulatory protein NosR
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -0.02
Kyte-Doolittle Hydrophobicity Value 0.074
Molecular Weight (kDa) 80.2
Isoelectric Point (pI) 7.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 168 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002237 (352 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3391
Search term: nosR

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular cloning, heterologous expression, and primary structure of the structural gene for the copper enzyme nitrous oxide reductase from denitrifying Pseudomonas stutzeri.
Viebrock A, Zumft WG
J Bacteriol 1988 Oct;170(10):4658-68
PubMed ID: 3049543
NosR, a membrane-bound regulatory component necessary for expression of nitrous oxide reductase in denitrifying Pseudomonas stutzeri.
Cuypers H, Viebrock-Sambale A, Zumft WG
J Bacteriol 1992 Aug;174(16):5332-9
PubMed ID: 1644760