Pseudomonas aeruginosa PAO1, PA3409 (hasS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3409
Name
hasS
Replicon chromosome
Genomic location 3817546 - 3818532 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252099.1
GI 15598605
Affymetrix PA3409_at
Entrez 878697
GenBank AAG06797.1
INSDC AAG06797.1
NCBI Locus Tag PA3409
protein_id(GenBank) gb|AAG06797.1|AE004762_3|gnl|PseudoCAP|PA3409
TIGR NTL03PA03409
UniParc UPI00000C59F7
UniProtKB Acc Q9HYJ6
UniProtKB ID Q9HYJ6_PSEAE
UniRef100 UniRef100_Q9HYJ6
UniRef50 UniRef50_Q9HYJ6
UniRef90 UniRef90_Q9HYJ6

Product

Feature Type CDS
Coding Frame 1
Product Name
HasS
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 7.22
Kyte-Doolittle Hydrophobicity Value -0.306
Molecular Weight (kDa) 35.5
Isoelectric Point (pI) 10.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 131 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002221 (353 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3409
Search term: hasS
Search term: HasS

Human Homologs

References

Characterization of five novel Pseudomonas aeruginosa cell-surface signalling systems.
Llamas MA, Mooij MJ, Sparrius M, Vandenbroucke-Grauls CM, Ratledge C, Bitter W
Mol Microbiol 2008 Jan;67(2):458-72
PubMed ID: 18086184
Pseudomonas aeruginosa possesses three distinct systems for sensing and using the host molecule haem.
Otero-Asman JR, García-García AI, Civantos C, Quesada JM, Llamas MA
Environ Microbiol 2019 Dec;21(12):4629-4647
PubMed ID: 31390127