Pseudomonas aeruginosa PAO1, PA3416

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3416
Name
Replicon chromosome
Genomic location 3822515 - 3823516 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_252106.1
GI 15598612
Affymetrix PA3416_at
DNASU PaCD00007501
Entrez 878692
GenBank AAG06804.1
INSDC AAG06804.1
NCBI Locus Tag PA3416
protein_id(GenBank) gb|AAG06804.1|AE004762_10|gnl|PseudoCAP|PA3416
TIGR NTL03PA03416
UniParc UPI00000C59FE
UniProtKB Acc Q9HYI9
UniProtKB ID Q9HYI9_PSEAE
UniRef100 UniRef100_U8NI93
UniRef50 UniRef50_P35488
UniRef90 UniRef90_A0A069QA02

Product

Feature Type CDS
Coding Frame 1
Product Name
probable pyruvate dehydrogenase E1 component, beta chain
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.46
Kyte-Doolittle Hydrophobicity Value 0.083
Molecular Weight (kDa) 36.1
Isoelectric Point (pI) 5.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 568 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002214 (793 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3416

Human Homologs

Ensembl 110, assembly GRCh38.p14
branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987]
E-value: 1.5e-65
Percent Identity: 41.4
Ensembl 110, assembly GRCh38.p14
branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987]
E-value: 1.5e-65
Percent Identity: 41.4

References

Identification and analysis of the genes coding for the putative pyruvate dehydrogenase enzyme complex in Acholeplasma laidlawii.
Wallbrandt P, Tegman V, Jonsson BH, Wieslander A
J Bacteriol 1992 Feb;174(4):1388-96
PubMed ID: 1735725