Pseudomonas aeruginosa PAO1, PA3538

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3538
Name
Replicon chromosome
Genomic location 3959955 - 3961037 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252228.1
GI 15598734
Affymetrix PA3538_at
Entrez 879008
GenBank AAG06926.1
INSDC AAG06926.1
NCBI Locus Tag PA3538
protein_id(GenBank) gb|AAG06926.1|AE004774_4|gnl|PseudoCAP|PA3538
TIGR NTL03PA03538
UniParc UPI00000C5A5D
UniProtKB Acc Q9HY73
UniProtKB ID Q9HY73_PSEAE
UniRef100 UniRef100_W0YTI2
UniRef50 UniRef50_Q0KDL1
UniRef90 UniRef90_A6V1Q7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ATP-binding component of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.27
Kyte-Doolittle Hydrophobicity Value -0.018
Molecular Weight (kDa) 39.2
Isoelectric Point (pI) 6.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002128 (530 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3538

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily G member 5 [Source:HGNC Symbol;Acc:HGNC:13886]
E-value: 1.3e-12
Percent Identity: 25.2

References

Identification of a locus involved in the utilization of iron by Haemophilus influenzae.
Sanders JD, Cope LD, Hansen EJ
Infect Immun 1994 Oct;62(10):4515-25
PubMed ID: 7927717