Pseudomonas aeruginosa PAO1, PA4241 (rpsM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4241
Name
rpsM
Replicon chromosome
Genomic location 4756492 - 4756848 (- strand)

Cross-References

RefSeq NP_252931.1
GI 15599437
Affymetrix PA4241_rpsM_at
DNASU PaCD00007839
Entrez 881818
GenBank AAG07629.1
INSDC AAG07629.1
NCBI Locus Tag PA4241
protein_id(GenBank) gb|AAG07629.1|AE004841_7|gnl|PseudoCAP|PA4241
TIGR NTL03PA04242
UniParc UPI00000C5C7F
UniProtKB Acc Q9HWF7
UniProtKB ID RS13_PSEAE
UniRef100 UniRef100_B7V665
UniRef50 UniRef50_O46912
UniRef90 UniRef90_A6UZL0

Product

Feature Type CDS
Coding Frame 1
Product Name
30S ribosomal protein S13
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 15.40
Kyte-Doolittle Hydrophobicity Value -0.681
Molecular Weight (kDa) 13.3
Isoelectric Point (pI) 11.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7UNV RIBOSOME 04/11/22 Pseudomonas aeruginosa 70S ribosome initiation complex bound to IF2-GDPCP (structure II-A) Escherichia coli; Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 2.7 ELECTRON MICROSCOPY 100.0
6SPE RIBOSOME 09/01/19 Pseudomonas aeruginosa 30s ribosome from a clinical isolate Pseudomonas aeruginosa 3.6 ELECTRON MICROSCOPY 100.0
7UNW RIBOSOME 04/11/22 Pseudomonas aeruginosa 70S ribosome initiation complex bound to IF2-GDPCP (structure II-B) Escherichia coli; Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 2.6 ELECTRON MICROSCOPY 100.0
6SPC RIBOSOME 09/01/19 Pseudomonas aeruginosa 30s ribosome from an aminoglycoside resistant clinical isolate Pseudomonas aeruginosa 2.95 ELECTRON MICROSCOPY 99.1
7UNR RIBOSOME 04/11/22 Pseudomonas aeruginosa 70S ribosome initiation complex bound to compact IF2-GDP (composite structure I-A) Escherichia coli; Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 2.9 ELECTRON MICROSCOPY 100.0
7UNU RIBOSOME 04/11/22 Pseudomonas aeruginosa 70S ribosome initiation complex bound to compact IF2-GDP (composite structure I-B) Escherichia coli; Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 2.9 ELECTRON MICROSCOPY 100.0
6SPG RIBOSOME 09/01/19 Pseudomonas aeruginosa 70s ribosome from a clinical isolate Pseudomonas aeruginosa 3.34 ELECTRON MICROSCOPY 100.0
6SPF RIBOSOME 09/01/19 Pseudomonas aeruginosa 70s ribosome from an aminoglycoside resistant clinical isolate Pseudomonas aeruginosa 2.89 ELECTRON MICROSCOPY 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 659 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001469 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4241
Search term: rpsM

Human Homologs

References

Nucleotide sequence of the alpha ribosomal protein operon of Escherichia coli.
Bedwell D, Davis G, Gosink M, Post L, Nomura M, Kestler H, Zengel JM, Lindahl L
Nucleic Acids Res 1985 Jun 11;13(11):3891-903
PubMed ID: 2989779
Placement of dinitrophenyl-modified ribosomal proteins in totally reconstituted Escherichia coli 30 S subunits. Localization of proteins S6, S13, S16, and S18 by immune electron microscopy.
Montesano-Roditis L, McWilliams R, Glitz DG, Olah TV, Perrault AR, Cooperman BS
J Biol Chem 1993 Sep 5;268(25):18701-9
PubMed ID: 8360163
Antisuppression by a mutation in rpsM(S13) giving a shortened ribosomal protein S13.
Faxén M, Walles-Granberg A, Isaksson LA
Biochim Biophys Acta 1994 May 17;1218(1):27-34
PubMed ID: 8193163