Pseudomonas aeruginosa PAO1, PA4949

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4949
Name
Synonym: yjeF
Replicon chromosome
Genomic location 5553572 - 5555080 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_253636.1
GI 15600142
Affymetrix PA4949_at
Entrez 878067
GenBank AAG08334.1
INSDC AAG08334.1
NCBI Locus Tag PA4949
protein_id(GenBank) gb|AAG08334.1|AE004907_12|gnl|PseudoCAP|PA4949
TIGR NTL03PA04950
UniParc UPI00000C5E8D
UniProtKB Acc Q9HUL5
UniProtKB ID Q9HUL5_PSEAE
UniRef100 UniRef100_Q9HUL5
UniRef50 UniRef50_A0A022PDU5
UniRef90 UniRef90_A0A022PDU5

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.69
Kyte-Doolittle Hydrophobicity Value 0.365
Molecular Weight (kDa) 51.5
Isoelectric Point (pI) 7.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 610 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004564 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4949

Human Homologs

References

The mutL repair gene of Escherichia coli K-12 forms a superoperon with a gene encoding a new cell-wall amidase.
Tsui HC, Zhao G, Feng G, Leung HC, Winkler ME
Mol Microbiol 1994 Jan;11(1):189-202
PubMed ID: 7511774