Pseudomonas aeruginosa PAO1, PA1664 (orfX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1664
Name
orfX
Replicon chromosome
Genomic location 1814995 - 1815135 (+ strand)

Cross-References

RefSeq NP_250355.1
GI 15596861
Affymetrix PA1664_at
DNASU PaCD00006753
Entrez 880635
GenBank AAG05053.1
INSDC AAG05053.1
NCBI Locus Tag PA1664
protein_id(GenBank) gb|AAG05053.1|AE004594_5|gnl|PseudoCAP|PA1664
TIGR NTL03PA01665
UniParc UPI00000C5436
UniProtKB Acc Q9I361
UniProtKB ID Q9I361_PSEAE
UniRef100 UniRef100_W0YQ08
UniRef50 UniRef50_Q87U84
UniRef90 UniRef90_W0YQ08

Product

Feature Type CDS
Coding Frame 1
Product Name
OrfX
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 2.16
Kyte-Doolittle Hydrophobicity Value -0.083
Molecular Weight (kDa) 4.9
Isoelectric Point (pI) 8.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database PseudoCAP
Category Hcp secretion island-2 encoded type VI secretion system (H2-T6SS)
Evidence ECO:0000317
genomic context evidence used in manual assertion
Host Organism Homo sapiens
Notes H2-T6SS rendered inactive via clpV2 deletion.
Reference 22665491

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in one genus

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003719 (396 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1664
Search term: orfX
Search term: OrfX

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295