Pseudomonas aeruginosa PAO1, PA1709 (popD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1709
Name
popD
Synonym: pepD
Replicon chromosome
Genomic location 1854849 - 1855736 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250400.1
GI 15596906
Affymetrix PA1709_popD_at
Entrez 879358
GenBank AAG05098.1
INSDC AAG05098.1
NCBI Locus Tag PA1709
protein_id(GenBank) gb|AAG05098.1|AE004597_12|gnl|PseudoCAP|PA1709
TIGR NTL03PA01710
UniParc UPI00000C5457
UniProtKB Acc Q9I323
UniProtKB ID Q9I323_PSEAE
UniRef100 UniRef100_W0YMR4
UniRef50 UniRef50_O50280
UniRef90 UniRef90_O50280

Product

Feature Type CDS
Coding Frame 1
Product Name
Translocator outer membrane protein PopD precursor
Product Name Confidence: Class 1
Synonyms PepD
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.51
Kyte-Doolittle Hydrophobicity Value -0.182
Molecular Weight (kDa) 31.3
Isoelectric Point (pI) 5.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
Extracellular Class 3
Host Associated
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0083
Category T3SS
Evidence
Host Organism
Notes
Reference 11372029

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 5 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003680 (308 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1709
Search term: popD

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
YopB and YopD constitute a novel class of Yersinia Yop proteins.
Håkansson S, Bergman T, Vanooteghem JC, Cornelis G, Wolf-Watz H
Infect Immun 1993 Jan;61(1):71-80
PubMed ID: 8418066
Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon.
Yahr TL, Mende-Mueller LM, Friese MB, Frank DW
J Bacteriol 1997 Nov;179(22):7165-8
PubMed ID: 9371466