Pseudomonas aeruginosa PAO1, PA1814 (kerV)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1814
Name
kerV
Replicon chromosome
Genomic location 1972195 - 1972956 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_250505.1
GI 15597011
Affymetrix PA1814_at
Entrez 880626
GenBank AAG05203.1
INSDC AAG05203.1
NCBI Locus Tag PA1814
protein_id(GenBank) gb|AAG05203.1|AE004608_2|gnl|PseudoCAP|PA1814
TIGR NTL03PA01815
UniParc UPI00000C54AD
UniProtKB Acc Q9I2T0
UniProtKB ID Q9I2T0_PSEAE
UniRef100 UniRef100_W0YP61
UniRef50 UniRef50_G8QBM3
UniRef90 UniRef90_W0YP61

Product

Feature Type CDS
Coding Frame 1
Product Name
KerV
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 9.49
Kyte-Doolittle Hydrophobicity Value -0.231
Molecular Weight (kDa) 28.4
Isoelectric Point (pI) 9.56

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database PseudoCAP
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Arabidopsis thaliana
Notes
Infection model Arabidopsis leaf infiltration model
Reference 19779606
Source 2
Database PseudoCAP
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Mus musculus
Notes
Infection model acute mouse pulmonary Infection model
Reference 19779606
Source 3
Database PseudoCAP
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Dictyostelium discoideum
Notes
Infection model amoeba phagocytosis assay
Reference 19779606
Source 4
Database PseudoCAP
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Drosophila melanogaster
Notes
Infection model Drosophila pricking model at 21 degrees Celsius
Reference 19779606

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 136 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003584 (560 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1814
Search term: kerV
Search term: KerV

Transposon Insertions in PAO1

Type ISphoA/hah insertion site
Mutant ID UWGC: 33840
Genomic Position 1972281
Position in ORF 87(762)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 8813
Genomic Position 1972221
Position in ORF 27(762)
Reference 14617778
Type ISphoA/hah insertion site
Mutant ID UWGC: 42701
Genomic Position 1972570
Position in ORF 376(762)
Reference 14617778

Transposon Insertions in Orthologs

References

The pathogenic properties of a novel and conserved gene product, KerV, in proteobacteria.
An D, Apidianakis Y, Boechat AL, Baldini RL, Goumnerov BC, Rahme LG
PLoS ONE 2009 Sep;4(9):e7167
PubMed ID: 19779606