Pseudomonas aeruginosa PAO1, PA1875

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1875
Name
Synonym: opmL
Replicon chromosome
Genomic location 2043847 - 2045124 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs
Commentinvolved in biofilm-specific resistance to a subset of antibiotics

Cross-References

RefSeq NP_250566.1
GI 15597072
Affymetrix PA1875_at
Entrez 882209
GenBank AAG05264.1
INSDC AAG05264.1
NCBI Locus Tag PA1875
protein_id(GenBank) gb|AAG05264.1|AE004613_9|gnl|PseudoCAP|PA1875
TIGR NTL03PA01876
UniParc UPI00000C54E4
UniProtKB Acc Q9I2M2
UniProtKB ID Q9I2M2_PSEAE
UniRef100 UniRef100_W0YSH8
UniRef50 UniRef50_A0A077K265
UniRef90 UniRef90_A0A077K265

Product

Feature Type CDS
Coding Frame 1
Product Name
probable outer membrane protein precursor
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.76
Kyte-Doolittle Hydrophobicity Value -0.579
Molecular Weight (kDa) 48.0
Isoelectric Point (pI) 5.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 163 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001555 (681 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1875

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295