Pseudomonas aeruginosa PAO1, PA1948 (rbsC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1948
Name
rbsC
Replicon chromosome
Genomic location 2133391 - 2134389 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250638.1
GI 15597144
Affymetrix PA1948_rbsC_at
DNASU PaCD00006872
Entrez 880795
GenBank AAG05336.1
INSDC AAG05336.1
NCBI Locus Tag PA1948
protein_id(GenBank) gb|AAG05336.1|AE004621_7|gnl|PseudoCAP|PA1948
TIGR NTL03PA01948
UniParc UPI00000C5524
UniProtKB Acc Q9I2F6
UniProtKB ID Q9I2F6_PSEAE
UniRef100 UniRef100_W0YPM4
UniRef50 UniRef50_Q4KEX2
UniRef90 UniRef90_A6V6L9

Product

Feature Type CDS
Coding Frame 1
Product Name
membrane protein component of ABC ribose transporter
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 5.40
Kyte-Doolittle Hydrophobicity Value 0.940
Molecular Weight (kDa) 34.0
Isoelectric Point (pI) 9.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 319 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003484 (488 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1948
Search term: rbsC

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular cloning and characterization of genes required for ribose transport and utilization in Escherichia coli K-12.
Iida A, Harayama S, Iino T, Hazelbauer GL
J Bacteriol 1984 May;158(2):674-82
PubMed ID: 6327617
The nucleotide sequences of the rbsD, rbsA, and rbsC genes of Escherichia coli K12.
Bell AW, Buckel SD, Groarke JM, Hope JN, Kingsley DH, Hermodson MA
J Biol Chem 1986 Jun 15;261(17):7652-8
PubMed ID: 3011793
Analysis of a ribose transport operon from Bacillus subtilis.
Woodson K, Devine KM
Microbiology (Reading) 1994 Aug;140 ( Pt 8):1829-38
PubMed ID: 7921236
The proteins encoded by the rbs operon of Escherichia coli: II. Use of chimeric protein constructs to isolate and characterize RbsC.
Zaitseva J, Zhang H, Binnie RA, Hermodson M
Protein Sci 1996 Jun;5(6):1100-7
PubMed ID: 8762141
A periplasmic intermediate in the extracellular secretion pathway of Pseudomonas aeruginosa exotoxin A.
Lu HM, Mizushima S, Lory S
J Bacteriol 1993 Nov;175(22):7463-7
PubMed ID: 7901198