Pseudomonas aeruginosa PAO1, PA1994

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1994
Name
Replicon chromosome
Genomic location 2181181 - 2181744 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250684.1
GI 15597190
Affymetrix PA1994_at
DNASU PaCD00006892
Entrez 880185
GenBank AAG05382.1
INSDC AAG05382.1
NCBI Locus Tag PA1994
protein_id(GenBank) gb|AAG05382.1|AE004626_1|gnl|PseudoCAP|PA1994
TIGR NTL03PA01994
UniParc UPI00000C5549
UniProtKB Acc Q9I2B5
UniProtKB ID Q9I2B5_PSEAE
UniRef100 UniRef100_Q9I2B5
UniRef50 UniRef50_Q9I2B5
UniRef90 UniRef90_Q9I2B5

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.83
Kyte-Doolittle Hydrophobicity Value -0.520
Molecular Weight (kDa) 21.6
Isoelectric Point (pI) 4.71

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2H1T UNKNOWN FUNCTION 05/16/06 Crystal structure of a duf1089 family protein (pa1994) from pseudomonas aeruginosa at 1.80 A resolution Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 45 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003441 (303 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1994

Human Homologs

References

The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism.
Bakolitsa C, Kumar A, McMullan D, Krishna SS, Miller MD, Carlton D, Najmanovich R, Abdubek P, Astakhova T, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Feuerhelm J, Grant JC, Grzechnik SK, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Marciano D, Morse AT, Nigoghossian E, Okach L, Oommachen S, Paulsen J, Reyes R, Rife CL, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA
Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 Oct 1;66(Pt 10):1211-7
PubMed ID: 20944213