Pseudomonas aeruginosa PAO1, PA2061 (sppD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA2061
Name
sppD
Replicon chromosome
Genomic location 2257722 - 2259332 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250751.1
GI 15597257
Affymetrix PA2061_at
Entrez 877832
GenBank AAG05449.1
INSDC AAG05449.1
NCBI Locus Tag PA2061
protein_id(GenBank) gb|AAG05449.1|AE004632_8|gnl|PseudoCAP|PA2061
TIGR NTL03PA02061
UniParc UPI00000C557E
UniProtKB Acc Q9I254
UniProtKB ID Q9I254_PSEAE
UniRef100 UniRef100_Q9I254
UniRef50 UniRef50_P33916
UniRef90 UniRef90_Q9I254

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter ATP-binding protein, SppD
Product Name Confidence: Class 1
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 17.18
Kyte-Doolittle Hydrophobicity Value -0.076
Molecular Weight (kDa) 59.2
Isoelectric Point (pI) 10.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003388 (303 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2061
Search term: sppD

Human Homologs

Ensembl 86, assembly GRCh38.p7
ATP binding cassette subfamily B member 10 [Source:HGNC Symbol;Acc:HGNC:41]
E-value: 7.4e-20
Percent Identity: 30.9

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 8663
Genomic Position 2258553
Position in ORF 832(1611)
Reference 14617778
Type Confirmed ISphoA/hah insertion site
Mutant ID UWGC: 46727
Genomic Position 2258358
Position in ORF 637(1611)
Reference 14617778

Transposon Insertions in Orthologs

References

Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14.
Pletzer D(1,)(2), Braun Y(3), Weingart H(3).
Antonie Van Leeuwenhoek. 2016 Jun;109(6):737-53.
PubMed ID: 26995781