Pseudomonas aeruginosa PAO1, PA2119

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2119
Name
Synonym: adh
Replicon chromosome
Genomic location 2330959 - 2332059 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250809.1
GI 15597315
Affymetrix PA2119_at
Entrez 879863
GenBank AAG05507.1
INSDC AAG05507.1
NCBI Locus Tag PA2119
protein_id(GenBank) gb|AAG05507.1|AE004639_5|gnl|PseudoCAP|PA2119
TIGR NTL03PA02119
UniParc UPI00000C55B6
UniProtKB Acc Q9I1Z6
UniProtKB ID Q9I1Z6_PSEAE
UniRef100 UniRef100_Q9I1Z6
UniRef50 UniRef50_Q0KDL6
UniRef90 UniRef90_A0A0A8RME7

Product

Feature Type CDS
Coding Frame 1
Product Name
alcohol dehydrogenase (Zn-dependent)
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.56
Kyte-Doolittle Hydrophobicity Value 0.099
Molecular Weight (kDa) 38.6
Isoelectric Point (pI) 5.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 555 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003315 (1429 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2119

Human Homologs

References

Alcohol dehydrogenase gene from Alcaligenes eutrophus: subcloning, heterologous expression in Escherichia coli, sequencing, and location of Tn5 insertions.
Jendrossek D, Steinbüchel A, Schlegel HG
J Bacteriol 1988 Nov;170(11):5248-56
PubMed ID: 2846513
Characterization of alcohol dehydrogenase genes of derepressible wild-type Alcaligenes eutrophus H16 and constitutive mutants.
Jendrossek D, Krüger N, Steinbüchel A
J Bacteriol 1990 Sep;172(9):4844-51
PubMed ID: 2144274