Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2133
|
Name |
|
Replicon | chromosome |
Genomic location | 2348538 - 2349395 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Overexpression of PA2133 results in impaired TTSS-mediated cytotoxicity |
RefSeq | NP_250823.1 |
GI | 15597329 |
Affymetrix | PA2133_at |
DNASU | PaCD00006943 |
Entrez | 877931 |
GenBank | AAG05521.1 |
INSDC | AAG05521.1 |
NCBI Locus Tag | PA2133 |
protein_id(GenBank) | gb|AAG05521.1|AE004640_10|gnl|PseudoCAP|PA2133 |
TIGR | NTL03PA02133 |
UniParc | UPI00000C55C3 |
UniProtKB Acc | Q9I1Y2 |
UniProtKB ID | Q9I1Y2_PSEAE |
UniRef100 | UniRef100_Q9I1Y2 |
UniRef50 | UniRef50_Q9I1Y2 |
UniRef90 | UniRef90_Q9I1Y2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Cyclic-guanylate-specific phosphodiesterase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | 8.51 |
Kyte-Doolittle Hydrophobicity Value | -0.238 |
Molecular Weight (kDa) | 31.9 |
Isoelectric Point (pI) | 9.46 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 381 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003342 (313 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2133
Search term: Cyclic-guanylate-specific phosphodiesterase
|
Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence.
Kulasakara H, Lee V, Brencic A, Liberati N, Urbach J, Miyata S, Lee DG, Neely AN, Hyodo M, Hayakawa Y, Ausubel FM, Lory S
Proc Natl Acad Sci U S A 2006 Feb 21;103(8):2839-44
PubMed ID: 16477007
|