Pseudomonas aeruginosa PAO1, PA2216

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2216
Name
Replicon chromosome
Genomic location 2436304 - 2437299 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250906.1
GI 15597412
Affymetrix PA2216_at
Entrez 878287
GenBank AAG05604.1
INSDC AAG05604.1
NCBI Locus Tag PA2216
protein_id(GenBank) gb|AAG05604.1|AE004648_3|gnl|PseudoCAP|PA2216
TIGR NTL03PA02216
UniParc UPI00000C5611
UniProtKB Acc Q9I1Q1
UniProtKB ID Q9I1Q1_PSEAE
UniRef100 UniRef100_W0YRU0
UniRef50 UniRef50_C3MG98
UniRef90 UniRef90_A6V5U8

Product

Feature Type CDS
Coding Frame 1
Product Name
2-keto-3-deoxy-D-arabinonate dehydratase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -8.98
Kyte-Doolittle Hydrophobicity Value -0.325
Molecular Weight (kDa) 36.3
Isoelectric Point (pI) 5.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 41 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003274 (453 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2216

Human Homologs

References

The Agrobacterium tumefaciens virulence gene chvE is part of a putative ABC-type sugar transport operon.
Kemner JM, Liang X, Nester EW
J Bacteriol 1997 Apr;179(7):2452-8
PubMed ID: 9079938
Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
Brouns SJ, Barends TR, Worm P, Akerboom J, Turnbull AP, Salmon L, van der Oost J
J Mol Biol 2008 May 30;379(2):357-71
PubMed ID: 18448118