Pseudomonas aeruginosa PAO1, PA2407 (fpvC)

Cytoplasmic Membrane
Outer Membrane
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
Replicon chromosome
Genomic location 2690160 - 2691113 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1


RefSeq NP_251097.1
GI 15597603
Affymetrix PA2407_at
DNASU PaCD00007047
Entrez 879560
GenBank AAG05795.1
INSDC AAG05795.1
NCBI Locus Tag PA2407
protein_id(GenBank) gb|AAG05795.1|AE004668_5|gnl|PseudoCAP|PA2407
UniParc UPI00000C56B6
UniProtKB Acc Q9I174
UniRef100 UniRef100_A0A069PX18
UniRef50 UniRef50_Q884F2
UniRef90 UniRef90_A6V577


Feature Type CDS
Coding Frame 1
Product Name
Product Name Confidence: Class 1
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) 6.68
Kyte-Doolittle Hydrophobicity Value -0.032
Molecular Weight (kDa) 34.3
Isoelectric Point (pI) 9.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 473 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003125 (497 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA2407
Search term: fpvC
Search term: FpvC

Transposon Insertions in PAO1

Type ISphoA/hah insertion site
Mutant ID UWGC: 30423
Genomic Position 2690399
Position in ORF 240(954)
Reference 14617778
Type ISphoA/hah insertion site
Mutant ID UWGC: 32055
Genomic Position 2690444
Position in ORF 285(954)
Reference 14617778

Transposon Insertions in Orthologs


Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
Iron Release from the Siderophore Pyoverdine in Pseudomonas aeruginosa Involves Three New Actors: FpvC, FpvG, and FpvH.
Ganne G, Brillet K, Basta B, Roche B, Hoegy F, Gasser V, Schalk IJ
ACS Chem. Biol. 2017 Apr;12(4):1056-1065
PubMed ID: 28192658
An ABC transporter with two periplasmic binding proteins involved in iron acquisition in Pseudomonas aeruginosa.
Brillet K, Ruffenach F, Adams H, Journet L, Gasser V, Hoegy F, Guillon L, Hannauer M, Page A, Schalk IJ
ACS Chem. Biol. 2012 Dec;7(12):2036-45
PubMed ID: 23009327